Auro (Amitabh Bachchan) is an intelligent and witty 13-year-old boy with an extremely rare genetic defect that causes accelerated aging. He suffers from a progeria-like syndrome. Mentally he is 13, very normal, but physically he looks five times older. In spite of his condition, Auro is a very happy boy. He lives with his mother Vidya (Vidya Balan) who is a gynecologist. Amol Arte (Abhishek Bachchan) is young, progressive and a full-of-ideals politician. He is out to prove to the world that 'politics' is not a bad word. He is a man with a mission. Auro is Amol's son.

LSD explores the human emotions of love, sex & betrayal through very candid points of view. Told through the chaos of the camera that has invaded all our lives - through handy cams filming home movies, security cameras shooting every inch of existence, mobile phones transmitting love messages, sting cameras uncovering uncomfortable truths.